Hi,

Yes, it's possible to separate Sales Order sequences by company in Odoo. By default, sequences can be shared across companies, but you can configure them to be company-specific, so each company maintains its own "Next Number."

1. Sequence of sales orders

Settings-> Technical -> Sequences & Identifiers ->Sequences

Example:

Company A 

Company B 

2. Create a sales order

Company A 

Company B

Hope it helps